An elastic second skin
Name
An elastic second skin.pdf
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1.38 MB
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Checksum (MD5)
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Author(s)
Yu, Betty
Kang, Soo-Young
Ramadurai, Nithin
Pilkenton, Morgan
Patel, Alpesh
Nashat, Amir
Sakamoto, Fernanda H.
Gilchrest, Barbara A.
Anderson, R. Rox
Anderson, Daniel Griffith
Date Issued
May 2016
Journal
Nature Materials
Publisher
Nature Publishing Group
Citation
Yu, Betty; Kang, Soo-Young; Akthakul, Ariya et al. “An Elastic Second Skin.” Nature Materials 15, 8 (May 2016): 911–918 © 2016 Macmillan Publishers Limited
Version
Author's final manuscript
Abstract
We report the synthesis and application of an elastic, wearable crosslinked polymer layer (XPL) that mimics the properties of normal, youthful skin. XPL is made of a tunable polysiloxane-based material that can be engineered with specific elasticity, contractility, adhesion, tensile strength and occlusivity. XPL can be topically applied, rapidly curing at the skin interface without the need for heat- or light-mediated activation. In a pilot human study, we examined the performance of a prototype XPL that has a tensile modulus matching normal skin responses at low strain (<40%), and that withstands elongations exceeding 250%, elastically recoiling with minimal strain-energy loss on repeated deformation. The application of XPL to the herniated lower eyelid fat pads of 12 subjects resulted in an average 2-grade decrease in herniation appearance in a 5-point severity scale. The XPL platform may offer advanced solutions to compromised skin barrier function, pharmaceutical delivery and wound dressings.
MIT Department
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Chemical Engineering
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1038/nmat4635
