Metabolic Teamwork in the Stem Cell Niche
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nihms909178.pdf
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348.96 KB
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Adobe PDF
Checksum (MD5)
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Author(s)
Roper, Jatin
Yilmaz, Omer
Date Issued
May 2017
Journal
Cell Metabolism
Publisher
Elsevier BV
Citation
Roper, Jatin, and Ömer H. Yilmaz. “Metabolic Teamwork in the Stem Cell Niche.” Cell Metabolism 25, no. 5 (May 2017): 993–994.
Version
Author's final manuscript
Abstract
Nearby cells can support stem cell differentiation, but the metabolic activities in stem cell niches are unknown. A recent study (Rodríguez-Colman et al., 2017) reveals a metabolic partnership in the intestinal stem cell niche: glycolysis in niche Paneth cells provides lactate to drive mitochondrial oxidative phosphorylation in intestinal stem cells.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
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DOI of Published Version
https://doi.org/10.1016/J.CMET.2017.04.019
