Aerosol-Assisted Plasma Deposition of Hydrophobic Polycations Makes Surfaces Highly Antimicrobial
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Author(s)
Liu, Harris
Kim, Yoojeong
Mello, Kerrianne
Lovaasen, John
Shah, Apoorva
Rice, Norman
Pappas, Daphne
Yim, Jacqueline H.
Klibanov, Alexander M
Date Issued
October 2013
Journal
Applied Biochemistry and Biotechnology
Publisher
Springer US
Citation
Liu, Harris et al. “Aerosol-Assisted Plasma Deposition of Hydrophobic Polycations Makes Surfaces Highly Antimicrobial.” Applied Biochemistry and Biotechnology 172.3 (2014): 1254–1264.
Version
Author's final manuscript
Abstract
The currently used multistep chemical synthesis for making surfaces antimicrobial by attaching to them hydrophobic polycations is replaced herein by an aerosol-assisted plasma deposition procedure. To this end, N,N-hexyl,methyl-PEI (HMPEI) is directly plasma-coated onto a glass surface. The resultant immobilized HMPEI coating has been thoroughly characterized and shown to be robust, bactericidal against Escherichia coli, and virucidal against human influenza virus.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Chemistry
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1007/s12010-013-0593-4
