Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2'-Deoxy and 2',3'-Dideoxynucleosides
Name
Shen Jamison AJC deoxygenation.pdf
Size
1.28 MB
Format
Adobe PDF
Checksum (MD5)
28ff292a98fc7491c3555a2e27875c41
Author(s)
Shen, Bo
Jamison, Timothy F.
Date Issued
November 2013
Journal
Australian Journal of Chemistry
Publisher
CSIRO Publishing
Citation
Shen, Bo, and Timothy F. Jamison. “Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2'-Deoxy and 2',3'-Dideoxynucleosides.” Australian Journal of Chemistry 66, no. 2 (2013): 157.
Version
Author's final manuscript
Abstract
A new photochemical flow reactor has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2′-deoxy and 2′,3′-dideoxynucleosides. The continuous flow format significantly improved both the efficiency and selectivity of the reaction, with the streamlined multi-step sequence directly furnishing the highly desired unprotected deoxynucleosides.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike 3.0
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DOI of Published Version
https://doi.org/10.1071/ch12426
