Speckle reduction in optical coherence tomography images using tissue viscoelasticity
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Kennedy-2011-Speckle reduction in.pdf
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Author(s)
Kennedy, Brendan F.
Curatolo, Andrea
Sampson, David D.
Hillman, Timothy Robert
Saunders, Christobel M.
Date Issued
February 2011
Journal
Journal of Biomedical Optics
Publisher
Society of Photo-optical Instrumentation Engineers
Citation
Kennedy, Brendan F. et al. “Speckle reduction in optical coherence tomography images using tissue viscoelasticity.” Journal of Biomedical Optics 16 (2011): 020506. © 2011 Society of Photo-Optical Instrumentation Engineers.
Version
Final published version
Abstract
We present a technique to reduce speckle in optical coherence tomography images of soft tissues. An average is formed over a set of B-scans that have been decorrelated by viscoelastic creep strain. The necessary correction for the deformation-induced spatial distortions between B-scans is achieved through geometrical co-registration using an affine transformation. Speckle reduction by up to a factor of 1.65 is shown in images of tissue-mimicking soft fibrin phantoms and excised human lymph node tissue with no observable loss of spatial resolution.
MIT Department
Massachusetts Institute of Technology. Spectroscopy Laboratory
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1117/1.3548239
