7.349 Stem Cells: A Cure or Disease?, Spring 2011
Author(s)
Bilodeau, Steve
Welstead, Grant
Alternative Title
Stem Cells: A Cure or Disease?
Date Issued
June 2011
Abstract
Have you ever considered going to a pharmacy to order some new cardiomyocytes (heart muscle cells) for your ailing heart? It might sound crazy, but recent developments in stem cell science have made this concept not so futuristic. In this course, we will explore the underlying biology behind the idea of using stem cells to treat disease, specifically analyzing the mechanisms that enable a single genome to encode multiple cell states ranging from neurons to fibroblasts to T cells. Overall, we hope to provide a comprehensive overview of this exciting new field of research and its clinical relevance. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Subjects
stem cells
stem cell therapy
cellular reprogramming
transdifferentiation
pluripotency
epigenetics
genome-wide sequencing
transcription-mediated reprogramming
embryonic stem cell technology
transcription factors
chromatin structure
H3K4me3
H3K27me3
histone deacetylase 1
RNAi screens
Oct4
cloning
Dolly
in vitro differentiation
regenerative medicine
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
This site (c) Massachusetts Institute of Technology 2023. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions.
Persistent DSpace Link
