Fabrication of drug delivery MEMS devices
Name
618741841-MIT.pdf
Description
Full printable version
Size
2.29 MB
Format
Adobe PDF
Checksum (MD5)
51b020537df9714221f8e3d00b6fc451
Author(s)
Lei, Wang S
Advisor(s)
Michael J. Cima.
Date Issued
2007
Publisher
Massachusetts Institute of Technology
Abstract
There is considerable amount of interest in the immediate treatment of personnel involved in high risk situations on the battlefield. A novel approach to drug delivery on the battlefield based on MEMS technology is discussed. By combining three separately fabricated layers, a single implantable drug delivery device capable of delivering up to 100 mm3 of a vasopressin solution was developed. In vitro release of vasopressin was observed and the I-V response of the bubble generator was characterized. Results show that the voltage at the time of release is ~11V while the current is ~0.35A, giving a power output of 3.79W. The time to total release of the drug was less than 2 minutes.
Description
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2007.
"May 2007." Cataloged from PDF version of thesis.
Includes bibliographical references (p. 19).
Subjects
Materials Science and Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
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