Conservation demands safe gene drive
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journal.pbio.2003850.pdf
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1.93 MB
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Adobe PDF
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3656a2ed833f22d903c96a302077f541
Author(s) •
Gemmell, Neil J.
Esvelt, Kevin Michael
Date Issued
November 2017
Journal
PLOS Biology
Publisher
Public Library of Science (PLoS)
Citation
Esvelt, Kevin M., and Neil J. Gemmell. “Conservation Demands Safe Gene Drive.” PLOS Biology, vol. 15, no. 11, Nov. 2017, p. e2003850. © 2017 Esvelt, Gemmell.
Version
Final published version
Abstract
Interest in developing gene drive systems to control invasive species is growing, with New Zealand reportedly considering the nascent technology as a way to locally eliminate the mammalian pests that threaten its unique flora and fauna. If gene drives successfully eradicated these invasive populations, many would rejoice, but what are the possible consequences? Here, we explore the risk of accidental spread posed by self-propagating gene drive technologies, highlight new gene drive designs that might achieve better outcomes, and explain why we need open and international discussions concerning a technology that could have global ramifications.
MIT Department
Massachusetts Institute of Technology. Media Laboratory
Program in Media Arts and Sciences (Massachusetts Institute of Technology)
Terms of Use
Creative Commons Attribution 4.0 International License
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DOI of Published Version
https://doi.org/10.1371/JOURNAL.PBIO.2003850