Leveraging Immunopeptidomics To Study and Combat Infectious Disease
Name
mSystems.00310-21.pdf
Description
Published version
Size
536.52 KB
Format
Adobe PDF
Checksum (MD5)
d6a15b136c6ee5f560daf21c9a0bc4cf
Author(s)
Leddy, Owen K
White, Forest M
Bryson, Bryan D
Date Issued
August 31, 2021
Journal
mSystems
Publisher
American Society for Microbiology
Version
Final published version
Abstract
T cells must recognize pathogen-derived peptides bound to major histocompatibility complexes (MHCs) in order to initiate a cell-mediated immune response against an infection, or to support the development of high-affinity antibody responses. Identifying antigens presented on MHCs by infected cells and professional antigen-presenting cells (APCs) during infection may therefore provide a route toward developing new vaccines.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Koch Institute for Integrative Cancer Research at MIT
Ragon Institute of MGH, MIT and Harvard
Center for Precision Cancer Medicine
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1128/msystems.00310-21
