Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections
Name
nihms-1682795.pdf
Description
Accepted version
Size
1.31 MB
Format
Unknown
Checksum (MD5)
6c503d5869fa6b84c08977852d6e915b
Author(s)
Kim, Byungji
Yang, Qinglin
Chan, Leslie W.
Bhatia, Sangeeta N.
Ruoslahti, Erkki
Sailor, Michael J.
Date Issued
February 2021
Journal
Nanoscale Horizons
Publisher
Royal Society of Chemistry (RSC)
Citation
Kim, Byungji, Yang, Qinglin, Chan, Leslie W, Bhatia, Sangeeta N, Ruoslahti, Erkki et al. 2021. "Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections." Nanoscale Horizons, 6 (4).
Version
Author's final manuscript
Abstract
RNAi-mediated immunotherapy provided by fusogenic porous silicon nanoparticles demonstrates superior therapeutic efficacy against both Gram-positive and Gram-negative bacterial infections compared with first-line antibiotics.
MIT Department
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1039/d0nh00624f
