Transdermal drug delivery by localized intervention
Name
Gowrishankar_Transdermal-Drug-Delivery.pdf
Size
3.14 MB
Format
Adobe PDF
Checksum (MD5)
26e21870bb1912e968ae60277783faa9
Author(s)
Weaver, James C.
Herndon, Terry O.
Gowrishankar, Thiruvallur R.
Date Issued
January 2009
Journal
IEEE Engineering in Medicine and Biology Magazine
Publisher
Institute of Electrical and Electronics Engineers
Citation
Gowrishankar, T.R., T.O. Herndon, and J.C. Weaver. “Transdermal drug delivery by localized intervention.” Engineering in Medicine and Biology Magazine, IEEE 28.1 (2009): 55-63. © Copyright 2009 IEEE
Version
Final published version
Abstract
Both field-confined skin electroporation and microscissioning offer minimally invasive methods for delivering drugs across skin and nail with minimal sensation. Both methods create high permeability pathways in a pain-free manner. These openings are similar in dimension to commonly experienced scratches and nicks on the skin. These localized openings provide pathways for sustained delivery of drugs either passively using a patch or actively using pressure or iontophoresis.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
http://dx.doi.org/10.1109/MEMB.2008.931016
