Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis)
Name
705_2014_Article_2162.pdf
Size
381.82 KB
Format
Adobe PDF
Checksum (MD5)
111c99189c43ed66f8bb7994b12897c5
Author(s)
Bui, Vuong Nghia
Mizutani, Tetsuya
Nguyen, Tung Hoang
Trinh, Dai Quang
Awad, Sanaa S. A.
Minoungou, Germaine L.
Yamamoto, Yu
Nakamura, Kikuyasu
Saito, Keisuke
Watanabe, Yukiko
Date Issued
July 2014
Journal
Archives of Virology
Publisher
Springer Vienna
Citation
Kitajima, Masaaki et al. “Occurrence and Genetic Diversity of Human Cosavirus in Influent and Effluent of Wastewater Treatment Plants in Arizona, United States.” Archives of Virology 160.7 (2015): 1775–1779.
Version
Author's final manuscript
Abstract
A hemagglutinating virus (8KS0813) was isolated from a red-necked stint. Hemagglutination inhibition and neutralization tests indicated that 8KS0813 was antigenically related to a prototype strain, APMV-6/duck/Hong Kong/18/199/77, but with an 8- and 16-fold difference, respectively, in their titers. The full genome sequence of 8KS0813 showed 98.6 % nucleotide sequence identity to that of APMV-6/duck/Italy/4524-2/07, which has been reported to belong to an APMV-6 subgroup, and showed less similarity to that of the prototype strain (70.6 % similarity). The growth of 8KS0813 and the prototype strain in four different cell cultures was greatly enhanced by adding trypsin. Interestingly, this virus induced syncytia only in Vero cells. 8KS0813 was identified as APMV-6/red-necked stint/Japan/8KS0813/08, but it is antigenically and genetically distinguishable from the prototype strain, suggesting that variant APMV-6 is circulating in migratory birds.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1007/s00705-014-2162-8
