Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds
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Jensen_Development automated.pdf
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Author(s)
Goodell, John R.
McMullen, Jonathan P.
Zaborenko, Nikolay
Maloney, Jason R.
Ho, Chuan-Xing
Jensen, Klavs F.
Porco, John A.
Beeler, Aaron B.
Date Issued
August 2009
Journal
Journal of Organic Chemistry
Publisher
American Chemical Society
Citation
Goodell, John R., Jonathan P. McMullen, Nikolay Zaborenko, Jason R. Maloney, Chuan-Xing Ho, Klavs F. Jensen, John A. Porco, and Aaron B. Beeler. "Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds." Journal of Organic Chemistry 74, no. 16 (August 21, 2009): 6169-6180.
Version
Author's final manuscript
Abstract
An automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo [3.2.1] octanoid scaffolds will be described.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/jo901073v
