Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens
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Author(s)
Husvogt, Lennart
Vardeh, Hilde
Sheykin, Yury
Faulkner-Jones, Beverly E.
Hornegger, Joachim
Brooker, Jeff
Cable, Alex
Connolly, James L.
Giacomelli, Michael
Yoshitake, Tadayuki
Date Issued
March 2016
Journal
Proceedings Volume 9712, Multiphoton Microscopy in the Biomedical Sciences XVI
Publisher
SPIE
Citation
Giacomelli, Michael G. et al. “Design of a Portable Wide Field of View GPU-Accelerated Multiphoton Imaging System for Real-Time Imaging of Breast Surgical Specimens.” Proceedings Volume 9712, Multiphoton Microscopy in the Biomedical Sciences XVI, 13-18 February, 2016, San Francisco, California, SPIE, 2016.
Version
Final published version
Abstract
We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtual H&E images for real-time assessment. The imaging system and virtual H&E rendering algorithm are demonstrated by imaging unfixed human breast tissue in a clinical setting. Keywords: multiphoton, histology, surgical pathology, H&E
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology. Research Laboratory of Electronics
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1117/12.2209241
