Design and manufacture of an ultra-high field ex vivo coil assembly
Name
813318772-MIT.pdf
Description
Full printable version
Size
21.8 MB
Format
Adobe PDF
Checksum (MD5)
cf8ce9df087850440197f32d4525a99b
Author(s)
Bridgers, Loren Daniel
Advisor(s)
Alexander Slocum.
Date Issued
2012
Publisher
Massachusetts Institute of Technology
Abstract
Magnetic Resonance based architectonic segmentation aims to detect variations in brain architecture that may provide incredible insight into diseases such as epilepsy, schizophrenia, dyslexia, and autism. Data from ex vivo scans is necessary for the development of automatic methods to detect these critical variations in vivo (1) (2). The optimization of ex vivo imaging requires the design and construction of special purpose instrumentation. This thesis presents the mechanical design and construction of a 32 channel ex vivo coil assembly for use in a 7 tesla MRI. The unit will be used for research at the Athinoula A. Martinos Center for Biomedical Imaging in Charlestown, Massachusetts. Also presented is the development and implementation of two unique low-cost tools to enhance the medical instrument prototyping process: a desktop vacuum casting system, and an automatic tool-path generation program for machining directly from STL files. Finally, an improved method and apparatus for degassing the tissue samples is developed and implemented leading to improvements in MRI image quality.
Description
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2012.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 78-79).
Subjects
Mechanical Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
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reproduction or distribution in any format is prohibited without written
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