Dipolar Recoupling in Rotating Solids
Name
nihms-2079045.pdf
Description
Accepted version
Size
14.81 MB
Format
Adobe PDF
Checksum (MD5)
63ea3a801609e7fa3e09cb655a3c0689
Author(s)
Ladizhansky, Vladimir
Palani, Ravi Shankar
Mardini, Michael
Griffin, Robert G
Date Issued
November 6, 2024
Journal
Chemical Reviews
Publisher
American Chemical Society
Citation
Dipolar Recoupling in Rotating Solids. Vladimir Ladizhansky, Ravi Shankar Palani, Michael Mardini, and Robert G. Griffin. Chemical Reviews 2024 124 (22), 12844-12917.
Version
Author's final manuscript
Abstract
Magic angle spinning (MAS) nuclear magnetic resonance (NMR) has evolved significantly over the past three decades and established itself as a vital tool for the structural analysis of biological macromolecules and materials. This review delves into the development and application of dipolar recoupling techniques in MAS NMR, which are crucial for obtaining detailed structural and dynamic information. We discuss a variety of homonuclear and heteronuclear recoupling methods which are essential for measuring spatial restraints and explain in detail the spin dynamics that these sequences generate. We also explore recent developments in high spinning frequency MAS, proton detection, and dynamic nuclear polarization, underscoring their importance in advancing biomolecular NMR. Our aim is to provide a comprehensive account of contemporary dipolar recoupling methods, their principles, and their application to structural biology and materials, highlighting significant contributions to the field and emerging techniques that enhance resolution and sensitivity in MAS NMR spectroscopy.
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1021/acs.chemrev.4c00373
