A Unified Point Process Framework for Assessing Heartbeat Dynamics and Cardiovascular Control
Name
Chen-2009-A Unified Point Process Framework for Assessing Heartbeat Dynamics and Cardiovascular Control.pdf
Size
422.74 KB
Format
Adobe PDF
Checksum (MD5)
174e98980300d5be3d971a24e08022bf
Author(s)
Chen, Zhe
Brown, Emery N.
Barbieri, Riccardo
Date Issued
May 2009
Journal
2009 IEEE 35th Annual Northeast Bioengineering Conference
Publisher
Institute of Electrical and Electronics Engineers
Citation
Zhe Chen, E.N. Brown, and R. Barbieri. “A unified point process framework for assessing heartbeat dynamics and cardiovascular control.” Bioengineering Conference, 2009 IEEE 35th Annual Northeast. 2009. 1-2. © 2009 IEEE
Version
Final published version
Abstract
We present a unified probabilistic point process framework to estimate and monitor the instantaneous heartbeat dynamics as related to specific cardiovascular control mechanisms and hemodynamics. Assessment of the model's statistics is established through the Wiener-Volterra theory and a multivariate autoregressive (AR) structure. A variety of instantaneous cardiovascular metrics, such as heart rate (HR), heart rate variability (HRV), respiratory sinus arrhythmia (RSA), and baroreceptor-cardiac reflex (baroreflex), can be rigorously derived within a parametric framework and instantaneously updated with an adaptive algorithm. Nonlinearity metrics, as well as the bispectrum of heartbeat intervals, can also be derived. We have applied the proposed point process framework to a number of recordings under different experimental protocols. Results reveal interesting dynamic trends across different posture/pharmacological/age/ heart disease conditions, pointing at our mathematical approach as a promising monitoring tool for an accurate, noninvasive assessment of a large spectrum of cardiovascular diseases and disorders, including hypertension and congestive heart disease.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1109/NEBC.2009.4967633
