Advancements in the synthesis of distorted tricoordinate phosphorus compounds and their use as platforms in reductive chemistries
Name
1142099151-MIT.pdf
Size
12.75 MB
Format
Adobe PDF
Checksum (MD5)
491c8711e58063514192f41d72aca4d0
Author(s)
Mattos, Jared Thomas.
Advisor(s)
Alexander T. Radosevich.
Date Issued
2019
Publisher
Massachusetts Institute of Technology
Abstract
This dissertation describes new reactivity of geometrically distorted [sigma]³ phosphorus compounds as well as attempts to synthesis new C₂v distorted [sigma]³ phosphorus compounds. Chapter two will describe the synthetic efforts towards synthesizing new [sigma]³ phosphorus compounds to provide new platforms to expand the chemistry of [sigma]³ phosphines. Chapter three presents a distorted phosphoramidate with a functionally hydridic P-H bond derived from the activation of water to generate equivalents of hydrogen. Chapter four explores the activation of both hydrazine and hydrazones by a distorted phosphoramidite and initial results in the use of these phosphoranes as platforms for hydrogen atom transfer chemistry. Chapter five presents a unique reaction in the formation of an oxazaphosphole that shows promise to allow for dearomatiztion of other aromatic substrates by a distorted phosphorus triamide. The research displayed here provides several novel approaches in the synthesis and use of [sigma]³ phosphorus compounds.
Description
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemistry, 2019
Cataloged from PDF version of thesis.
Includes bibliographical references.
Subjects
Chemistry.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
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