An Organic Chemist’s Guide to N -Nitrosamines: Their Structure, Reactivity, and Role as Contaminants
Name
acs.joc.0c02774.pdf
Description
Published version
Size
4.2 MB
Format
Unknown
Checksum (MD5)
75bc661db16a5a6b79a4bbcfdecdb09e
Author(s)
Beard, Jessica C
Swager, Timothy M
Date Issued
2021
Journal
Journal of Organic Chemistry
Publisher
American Chemical Society (ACS)
Citation
Beard, Jessica C and Swager, Timothy M. 2021. "An Organic Chemist’s Guide to N -Nitrosamines: Their Structure, Reactivity, and Role as Contaminants." Journal of Organic Chemistry, 86 (3).
Version
Final published version
Abstract
© 2021 American Chemical Society. N-Nitrosamines are a class of compounds notorious both for the potent carcinogenicity of many of its members and for their widespread occurrence throughout the human environment, from air and water to our diets and drugs. Considerable effort has been dedicated to understanding N-nitrosamines as contaminants, and methods for their prevention, remediation, and detection are ongoing challenges. Understanding the chemistry of N-nitrosamines will be key to addressing these challenges. To facilitate such understanding, we focus in this Perspective on the structure, reactivity, and synthetic applications of N-nitrosamines with an emphasis on alkyl N-nitrosamines. The role of N-nitrosamines as water contaminants and the methods for their detection are also discussed.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1021/ACS.JOC.0C02774
