Brain microelectrode array systems
Name
53324115-MIT.pdf
Description
Full printable version
Size
19.88 MB
Format
Adobe PDF
Checksum (MD5)
6bb1fad6928b679ce1c8eb9a16127e9b
Author(s)
Fofonoff, Timothy Andrew, 1977-
Advisor(s)
Ian W. Hunter.
Date Issued
2003
Publisher
Massachusetts Institute of Technology
Abstract
New methods for manufacturing microelectrode array assemblies, passive devices designed for intracortically recording brain activity in nonhuman primates, were developed and explored. Wire electrical discharge machining (EDM), chemical etching, micromilling, parylene deposition, and laser ablation were some of the processes employed to create distinctive microstructures with fine features and high aspect ratios. These microstructures, constructed from a variety of metals and polymers, were assembled to form the mechanical front end of a brain-machine interface (BMI). The developed techniques were used to produce microelectrode array assemblies for the Telemetric Electrode Array System (TEAS), a surgically implantable wireless device to be used for motor cortex studies in nonhuman primates. Two prototypes of the TEAS microelectrode array assemblies were implanted in animals in order to validate the design and the manufacturing processes. Neural activity was successfully recorded. Future work is required in order to refine and further automate the processes. Similar devices could one day develop into neural prostheses for clinical use by outputting motor intent captured from brain activity in paralyzed patients.
Description
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2003.
Includes bibliographical references (leaves 110-114).
Subjects
Mechanical Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
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