HiGlass: web-based visual exploration and analysis of genome interaction maps
Name
13059_2018_Article_1486.pdf
Size
3.12 MB
Format
Adobe PDF
Checksum (MD5)
1d784b63036f9fc8f5bdad8e35a8e4b8
Author(s)
Kerpedjiev, Peter
Lekschas, Fritz
McCallum, Chuck
Dinkla, Kasper
Strobelt, Hendrik
Luber, Jacob M
Ouellette, Scott B
Azhir, Alaleh
Kumar, Nikhil
Hwang, Jeewon
Date Issued
August 2018
Journal
Genome Biology
Publisher
BioMed Central
Citation
Kerpedjiev, Peter, et al. “HiGlass: Web-Based Visual Exploration and Analysis of Genome Interaction Maps.” Genome Biology, vol. 19, no. 1, Dec. 2018.
Version
Final published version
Abstract
We present HiGlass, an open source visualization tool built on web technologies that provides a rich interface for rapid, multiplex, and multiscale navigation of 2D genomic maps alongside 1D genomic tracks, allowing users to combine various data types, synchronize multiple visualization modalities, and share fully customizable views with others. We demonstrate its utility in exploring different experimental conditions, comparing the results of analyses, and creating interactive snapshots to share with collaborators and the broader public. HiGlass is accessible online at
http://higlass.io
and is also available as a containerized application that can be run on any platform.
MIT Department
Institute for Medical Engineering and Science
Massachusetts Institute of Technology. Computational and Systems Biology Program
Massachusetts Institute of Technology. Department of Physics
Terms of Use
Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1186/s13059-018-1486-1
