7.343 When Development Goes Awry: How Cancer Co-opts Mechanisms of Embryogensis, Fall 2009
Author(s)
Meylan, Etienne
Oliver, Trudy
Alternative Title
When Development Goes Awry: How Cancer Co-opts Mechanisms of Embryogensis
Date Issued
December 2009
Abstract
During this course, we will study the similarities between cancer and normal development to understand how tumors co-opt normal developmental processes to facilitate cancer initiation, maintenance and progression. We will examine critical signaling pathways that govern these processes and, importantly, how some of these pathways hold promise as therapeutic targets for cancer treatment. We will discuss how future treatments might be personalized to target cancer cells in specific patients. We will also consider examples of newly-approved drugs that have dramatically helped patients combat this devastating disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Subjects
cancer
embryogenesis
sonic hedgehog
tumor
signaling
proto-oncogene
Kras
apoptosis
self-renewal
regeneration
angiogenesis
VEGF
tumorigenesis
metastasis
microRNA
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
This site (c) Massachusetts Institute of Technology 2023. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions.
Persistent DSpace Link
