Engineering transcription-based digital logic devices
Name
RPS-ICSB_2005.pdf
Size
182.25 KB
Format
Adobe PDF
Checksum (MD5)
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Author(s)
Shetty, Reshma P.
Knight, Thomas F. Jr
Date Issued
October 20, 2005
Publisher
Sixth International Conference on Systems Biology
Citation
R.P. Shetty and T.F. Knight Jr. Engineering transcription-based digital logic. Sixth International Conference on Systems Biology, 2005.
Abstract
The goal of Synthetic Biology is to engineer systems from biological parts. One class of systems are those whose purpose is to process information. My work seeks to build transcription-based devices for use in combinational digital logic. Preliminary characterization experiments show that existing devices fall short of desired device behavior. I propose to develop a novel implementation of transcription-based logic by designing synthetic transcription factors from well-characterized DNA binding and dimerization domains. Initial modeling work serves to inform design of these devices.
Description
Poster presented at the 2005 ICSB meeting, held at Harvard Medical School in Boston, MA.
Subjects
Synthetic Biology
Engineered Biological Systems
Transcription-based logic
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Persistent DSpace Link
