Nanoscale interfaces to biology
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COCHBI-S-10-00032-2.pdf
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Main article
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233.86 KB
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Author(s) •
Park, Sunho
Hamad, Kimberly S.
Date Issued
October 2010
Journal
Current Opinion in Chemical Biology
Publisher
Elsevier
Citation
Park, Sunho, and Kimberly Hamad-Schifferli. “Nanoscale Interfaces to Biology.” Current Opinion in Chemical Biology 14, no. 5 (October 2010): 616–622.
Version
Author's final manuscript
Abstract
Nanotechnology has held great promise for revolutionizing biology. The biological behavior of nanomaterials depends primarily on how they interface to biomolecules and their surroundings. Unfortunately, interface issues like non-specific adsorption are still the biggest obstacles to the success of nanobiotechnology and nanomedicine, and have held back widespread practical use of nanotechnology in biology. Not only does the biological interface of nanoparticles (NPs) need to be understood and controlled, but also NPs must be treated as biological entities rather than inorganic ones. Furthermore, one can adopt an engineering perspective of the NP–biological interface, realizing that it has unique, exploitable properties.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Mechanical Engineering
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Creative Commons Attribution-NonCommercial-NoDerivs License
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DOI of Published Version
https://doi.org/10.1016/j.cbpa.2010.06.186