CRISPR Interference Reveals That All- Trans -Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A
Name
mbio.03683-21.pdf
Description
Published version
Size
4.05 MB
Format
Adobe PDF
Checksum (MD5)
fb179c5ac160f89464dacbe7397aa2af
Author(s)
Babunovic, Gregory H
DeJesus, Michael A
Bosch, Barbara
Chase, Michael R
Barbier, Thibault
Dickey, Amy K
Bryson, Bryan D
Rock, Jeremy M
Fortune, Sarah M
Date Issued
2022
Journal
mBio
Publisher
American Society for Microbiology
Citation
Babunovic, Gregory H, DeJesus, Michael A, Bosch, Barbara, Chase, Michael R, Barbier, Thibault et al. 2022. "CRISPR Interference Reveals That All- Trans -Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A." mBio, 13 (1).
Version
Final published version
Abstract
Tuberculosis, caused by the bacterium Mycobacterium tuberculosis , is a leading cause of death due to infectious disease. Improving the immune response to tuberculosis holds promise for fighting the disease but is limited by our lack of knowledge as to how the immune system kills M. tuberculosis .
Tuberculosis, caused by the bacterium Mycobacterium tuberculosis , is a leading cause of death due to infectious disease. Improving the immune response to tuberculosis holds promise for fighting the disease but is limited by our lack of knowledge as to how the immune system kills M. tuberculosis .
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Terms of Use
Creative Commons Attribution 4.0 International license
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DOI of Published Version
https://doi.org/10.1128/MBIO.03683-21
