Microfluidics in structured multimaterial fibers
Name
E10830.full.pdf
Description
Published version
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1.68 MB
Format
Adobe PDF
Checksum (MD5)
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Author(s) • • • • • •
Yuan, Rodger
Lee, Jaemyon
Su, Hao-Wei
Levy, Etgar Claude
Khudiyev, Tural
Voldman, Joel
Fink, Yoel
Date Issued
October 2018
Journal
Proceedings of the National Academy of Sciences of the United States of America
Publisher
Proceedings of the National Academy of Sciences
Citation
Yuan, Rodger et al., "Microfluidics in structured multimaterial fibers." Proceedings of the National Academy of Sciences of the United States of America 115, 46 (November 2018): p. E10830-E10838 doi. 10.1073/pnas.1809459115 ©2018 Authors
Version
Final published version
Abstract
Traditional fabrication techniques for microfluidic devices utilize a planar chip format that possesses limited control over the geometry of and materials placement around microchannel cross-sections. This imposes restrictions on the design of flow fields and external forces (electric, magnetic, piezoelectric, etc.) that can be imposed onto fluids and particles. Here we report a method of fabricating microfluidic channels with complex cross-sections. A scaled-up version of a microchannel is dimensionally reduced through a thermal drawing process, enabling the fabrication of meters-long microfluidic fibers with nonrectangular cross-sectional shapes, such as crosses, five-pointed stars, and crescents. In addition, by codrawing compatible materials, conductive domains can be integrated at arbitrary locations along channel walls. We validate this technology by studying unexplored regimes in hydrodynamic flow and by designing a high-throughput cell separation device. By enabling these degrees of freedom in microfluidic device design, fiber microfluidics provides a method to create microchannel designs that are inaccessible using planar techniques. ©2018
MIT Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology. Research Laboratory of Electronics
Massachusetts Institute of Technology. Microsystems Technology Laboratories
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DOI of Published Version
https://doi.org/10.1073/PNAS.1809459115