Mechanics of Mineralized Collagen Fibrils upon Transient Loads
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2009.02984.pdf
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Accepted version
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333.4 KB
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Author(s)
Milazzo, Mario
Jung, Gang Seob
Danti, Serena
Buehler, Markus J
Date Issued
June 2020
Journal
ACS Nano
Publisher
American Chemical Society (ACS)
Citation
Mario Milazzo, Gang Seob Jung, Serena Danti, and Markus J. Buehler, Mechanics of Mineralized Collagen Fibrils upon Transient Loads, ACS Nano 2020 14 (7), 8307-8316. © 2020 American Chemical Society
Version
Author's final manuscript
Abstract
Collagen is a key structural protein in the human body, which undergoes mineralization during the formation of hard tissues. Earlier studies have described the mechanical behavior of bone at different scales, highlighting material features across hierarchical structures. Here we present a study that aims to understand the mechanical properties of mineralized collagen fibrils upon tensile/compressive transient loads, investigating how the kinetic energy propagates and it is dissipated at the molecular scale, thus filling a gap of knowledge in this area. These specific features are the mechanisms that nature has developed to passively dissipate stress and prevent structural failures. In addition to the mechanical properties of the mineralized fibrils, we observe distinct nanomechanical behaviors for the two regions (i.e., overlap and gap) of the D-period to highlight the effect of the mineralization. We notice decreasing trends for both wave speeds and Young's moduli over input velocity with a marked strengthening effect in the gap region due to the accumulation of the hydroxyapatite. In contrast, the dissipative behavior is not affected by either loading conditions or the mineral percentage, showing a stronger damping effect upon faster inputs compatible to the bone behavior at the macroscale. Our results offer insights into the dissipative behavior of mineralized collagen composites to design and characterize bioinspired composites for replacement devices (e.g., prostheses for sound transmission or conduction) or optimized structures able to bear transient loads, for example, impact, fatigue, in structural applications.
MIT Department
Massachusetts Institute of Technology. Laboratory for Atomistic and Molecular Mechanics
Massachusetts Institute of Technology. Center for Computational Science and Engineering
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DOI of Published Version
https://doi.org/10.1021/ACSNANO.0C02180
