Unexpected Formation of Hexasubstituted Arenes through a 2-fold Palladium-Mediated Ligand Arylation
Name
nihms-1055832.pdf
Description
Accepted version
Size
1.46 MB
Format
Unknown
Checksum (MD5)
bf2d9110e252f2aa3b96503ae2aea5c6
Author(s)
Wagen, Corin C
Ingoglia, Bryan Taylor
Buchwald, Stephen Leffler
Date Issued
2019
Journal
Journal of Organic Chemistry
Publisher
American Chemical Society (ACS)
Version
Author's final manuscript
Abstract
© 2019 American Chemical Society. A rearrangement reaction of biarylphosphine-supported Pd(II) complexes was employed to synthesize 1,3,5-triaryl 2,4,6-triisopropylbenzene compounds, a class of molecules that has not previously been reported. The strain of the central hexasubstituted ring was investigated via X-ray crystallography.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/ACS.JOC.9B02091
