Gamma and beta bursts during working memory readout suggest roles in its volitional control
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s41467-017-02791-8.pdf
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Author(s)
Herman, Pawel
Lundqvist, Lars Mikael
Warden, Melissa
Brincat, Scott Louis
Miller, Earl K
Date Issued
January 2018
Journal
Nature Communications
Publisher
Nature Publishing Group
Citation
Lundqvist, Mikael et al. “Gamma and Beta Bursts During Working Memory Readout Suggest Roles in Its Volitional Control.” Nature Communications 9, 1 (January 2018) © 2018 The Author(s)
Version
Final published version
Abstract
Working memory (WM) activity is not as stationary or sustained as previously thought. There are brief bursts of gamma (~50-120 Hz) and beta (~20-35 Hz) oscillations, the former linked to stimulus information in spiking. We examined these dynamics in relation to readout and control mechanisms of WM. Monkeys held sequences of two objects in WM to match to subsequent sequences. Changes in beta and gamma bursting suggested their distinct roles. In anticipation of having to use an object for the match decision, there was an increase in gamma and spiking information about that object and reduced beta bursting. This readout signal was only seen before relevant test objects, and was related to premotor activity. When the objects were no longer needed, beta increased and gamma decreased together with object spiking information. Deviations from these dynamics predicted behavioral errors. Thus, beta could regulate gamma and the information in WM.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Picower Institute for Learning and Memory
Terms of Use
Attribution 4.0 International (CC BY 4.0)
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1038/s41467-017-02791-8
