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  4. Architecture for Directed Transport of Superparamagnetic Microbeads in a Magnetic Domain Wall Routing Network

Architecture for Directed Transport of Superparamagnetic Microbeads in a Magnetic Domain Wall Routing Network

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Author(s)
Rapoport, Elizabeth Ashera
•
Beach, Geoffrey Stephen
Date Issued
August 2017
Journal
Scientific Reports
Publisher
Nature Publishing Group
Citation
Rapoport, Elizabeth, and Beach, Geoffrey S. D. “Architecture for Directed Transport of Superparamagnetic Microbeads in a Magnetic Domain Wall Routing Network.” Scientific Reports 7, 1 (August 2017) © 2017 The Author(s)
Version
Final published version
Abstract
Directed transport of biological species across the surface of a substrate is essential for realizing lab-on-chip technologies. Approaches that utilize localized magnetic fields to manipulate magnetic particles carrying biological entities are attractive owing to their sensitivity, selectivity, and minimally disruptive impact on biomaterials. Magnetic domain walls in magnetic tracks produce strong localized fields and can be used to capture, transport, and detect individual superparamagnetic microbeads. The dynamics of magnetic microbead transport by domain walls has been well studied. However, demonstration of more complex functions such as selective motion and sorting using continuously driven domain walls in contiguous magnetic tracks is lacking. Here, a junction architecture is introduced that allows for branching networks in which superparamagnetic microbeads can be routed along dynamically-selected paths by a combination of rotating in-plane field for translation, and a pulsed out-of-plane field for path selection. Moreover, experiments and modeling show that the select-field amplitude is bead-size dependent, which allows for digital sorting of multiple bead populations using automated field sequences. This work provides a simple means to implement complex routing networks and selective transport functionalities in chip-based devices using magnetic domain wall conduits.
MIT Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Terms of Use
Creative Commons Attribution 4.0 International License
http://creativecommons.org/licenses/by/4.0/
Persistent DSpace Link
http://hdl.handle.net/1721.1/111659
DOI of Published Version
https://doi.org/10.1038/s41598-017-10149-9
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