Cell-laden Microengineered and Mechanically Tunable Hybrid Hydrogels of Gelatin and Graphene Oxide
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Khademhosseini_Cell-laden Microengineered.pdf
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Author(s)
Shin, Su Ryon
Aghaei-Ghareh-Bolagh, Behnaz
Dang, Tram T.
Topkaya, Seda Nur
Gao, Xiguang
Yang, Seung Yun
Jung, Sung Mi
Oh, Jong Hyun
Dokmeci, Mehmet
Tang, Xiaowu (Shirley)
Date Issued
November 2013
Journal
Advanced Materials
Publisher
John Wiley & Sons, Inc
Citation
Shin, Su Ryon, Behnaz Aghaei-Ghareh-Bolagh, Tram T. Dang, Seda Nur Topkaya, Xiguang Gao, Seung Yun Yang, Sung Mi Jung, et al. “Cell-Laden Microengineered and Mechanically Tunable Hybrid Hydrogels of Gelatin and Graphene Oxide.” Advanced Materials 25, no. 44 (November 2013): 6385–6391.
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Author's final manuscript
Abstract
Incorporating graphene oxide inside GelMA hydrogels enhances their mechanical properties and reduces UV-induced cell damage while preserving their favorable characteristics for 3D cell encapsulation. NIH-3T3 fibroblasts encapsulated in GO-GelMA microgels demonstrate excellent cellular viability, proliferation, spreading, and alignment. GO reinforcement combined with a multi-stacking approach offers a facile engineering strategy for the construction of complex artificial tissues.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1002/adma.201301082
