Instrumentation to characterize needle insertion into biological tissue
Name
51805331-MIT.pdf
Description
Full printable version
Size
9.33 MB
Format
Adobe PDF
Checksum (MD5)
1ad669f559036e599d67b04b0c5f8f69
Author(s)
Chan, Wilson (Wilson Sian Chew), 1976-
Advisor(s)
Ian W. Hunter.
Date Issued
2002
Publisher
Massachusetts Institute of Technology
Abstract
The Transdermal Drug Delivery Project in the BioInstrumentation Laboratory involves the design of a device to deliver drugs through the human skin using micro needles. It is crucial to characterize the insertion of micro needles into biological tissues. Hence, instrumentation will be designed and fabricated for the characterization of micro needle insertion. This thesis focuses on the design and fabrication of such instrumentation. The instrument is multi-modal, multi-axis, mobile and compact. It is capable of precise insertion positioning and acquiring accurate insertion force data. Characterization of micro needle insertion into biological tissues is done successfully using the data acquired by this instrument and an existing physical force model.
Description
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2002.
Includes bibliographical references (leaves 52-53).
Subjects
Mechanical Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
Terms of Use
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