Anatomical atlas-guided diffuse optical tomography of brain activation
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Grimson_Anatomical atlas.pdf
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3.12 MB
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Adobe PDF
Checksum (MD5)
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Author(s)
Custo, Anna
Boas, David A.
Tsuzuki, Daisuke
Dan, Ippeita
Mesquita, Rickson
Fischl, Bruce
Wells, William M.
Date Issued
July 2009
Journal
NeuroImage
Publisher
Elsevier
Citation
Custo, Anna et al. “Anatomical Atlas-guided Diffuse Optical Tomography of Brain Activation.” NeuroImage 49.1 (2010): 561–567.
Version
Author's final manuscript
Abstract
We describe a neuroimaging protocol that utilizes an anatomical atlas of the human head to guide diffuse optical tomography of human brain activation. The protocol is demonstrated by imaging the hemodynamic response to median-nerve stimulation in three healthy subjects, and comparing the images obtained using a head atlas with the images obtained using the subject-specific head anatomy. The results indicate that using the head atlas anatomy it is possible to reconstruct the location of the brain activation to the expected gyrus of the brain, in agreement with the results obtained with the subject-specific head anatomy. The benefits of this novel method derive from eliminating the need for subject-specific head anatomy and thus obviating the need for a subject-specific MRI to improve the anatomical interpretation of diffuse optical tomography images of brain activation.
MIT Department
Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike 3.0
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DOI of Published Version
https://doi.org/10.1016/j.neuroimage.2009.07.033
