Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs
Name
nihms-1537190.pdf
Description
Accepted version
Size
2.2 MB
Format
Adobe PDF
Checksum (MD5)
2903fb7695a4a786439809d270c8ef87
Author(s)
Song, Yuelin
van den Berg, Patrick R.
Markoulaki, Styliani
Soldner, Frank
Dall’Agnese, Alessandra
Henninger, Jonathan E.
Drotar, Jesse
Rosenau, Nicholas
Cohen, Malkiel A.
Young, Richard A.
Date Issued
August 2019
Journal
Molecular Cell
Publisher
Elsevier BV
Citation
Song, Yuelin et al. "Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs." Molecular Cell 75, 5 (September 2019): P905-920.e6 © 2019 Elsevier Inc
Version
Author's final manuscript
Abstract
Song et al. used an allelic reporter approach to show super-enhancers allelic DNA methylation dynamics underlies locus-specific heterogeneity, which functionally impacts transcription and cellular states of mouse embryonic stem cells.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.molcel.2019.06.045
