Palladium–peptide oxidative addition complexes for bioconjugation
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d2sc04074c.pdf
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Published version
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Author(s) • • • • • • • •
Rojas, Anthony J
Wolfe, Justin M
Dhanjee, Heemal H
Buslov, Ivan
Truex, Nicholas L
Liu, Richard Y
Massefski, Walter
Pentelute, Bradley L
Buchwald, Stephen L
Date Issued
October 19, 2022
Journal
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Citation
Rojas, Anthony J, Wolfe, Justin M, Dhanjee, Heemal H, Buslov, Ivan, Truex, Nicholas L et al. 2022. "Palladium–peptide oxidative addition complexes for bioconjugation." Chemical Science, 13 (40).
Version
Final published version
Abstract
Peptides bearing palladium oxidative addition complexes can be synthesized from the parent aryl halide containing substrates and react with thiol functional groups of small molecules, peptides, and proteins at low micromolar concentrations.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Koch Institute for Integrative Cancer Research at MIT
Massachusetts Institute of Technology. Center for Environmental Health Sciences
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Creative Commons Attribution NonCommercial License 3.0
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DOI of Published Version
https://doi.org/10.1039/d2sc04074c