The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
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12915_2021_Article_1027.pdf
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Author(s)
Abbott, Keene L.
Vander Heiden, Matthew G.
Date Issued
May 10, 2021
Publisher
BioMed Central
Citation
BMC Biology. 2021 May 10;19(1):92
Version
Final published version
Abstract
Abstract
The extent to which tumors acquire nutrients from dietary sources as opposed to from the breakdown of host tissues is not known. In this issue of BMC Biology, Holland et al. report an approach where food sources with different isotope labeled carbon ratios can be used to answer this question, and find that tumors arising in Drosophila melanogaster procure most of their nutrients from the host.
MIT Department
Koch Institute for Integrative Cancer Research at MIT
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Creative Commons Attribution
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DOI of Published Version
https://doi.org/10.1186/s12915-021-01027-y
