HST.523J / 2.785J / 3.97J / 20.411J Cell-Matrix Mechanics, Spring 2004
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hst-523j-spring-2004/contents/index.htm
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34.01 KB
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Checksum (MD5)
65f943884aea5ca42d33f3856e79e560
Author(s)
Yannas, Ioannis
Spector, Myron
Alternative Title
Cell-Matrix Mechanics
Date Issued
June 2004
Abstract
Mechanical forces play a decisive role during development of tissues and organs, during remodeling following injury as well as in normal function. A stress field influences cell function primarily through deformation of the extracellular matrix to which cells are attached. Deformed cells express different biosynthetic activity relative to undeformed cells. The unit cell process paradigm combined with topics in connective tissue mechanics form the basis for discussions of several topics from cell biology, physiology, and medicine.
Subjects
cell
tissue
organ
unit cell process
cell matrix
tissue structure
extracellular matrix
adhesion protein
integrin
cell force
cell contraction
healing
skin
scar
tendon
ligament
cartilage
bone
collagen
muscle
nerve
implant
HST.523J
HST.523
2.785J
2.785
3.97J
3.97
20.411J
20.411
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Massachusetts Institute of Technology. Department of Mechanical Engineering
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