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A comparative genomics multitool for scientific discovery and conservation
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A comparative genomics multitool for scientific discovery and conservation
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Name
s41586-020-2876-6.pdf
Description
Published version
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Size
5.14 MB
Format
Adobe PDF
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sword-2021-07-20T17:44:07.original.xml (130 B)
Original SWORD entry document
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Date Issued
November 12, 2020
Journal
Nature
Publisher
Springer Science and Business Media LLC
Version
Final published version
Abstract
© 2020, The Author(s). The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of which all but 9 are previously uncharacterized, and describe a whole-genome alignment of 240 species of considerable phylogenetic diversity, comprising representatives from more than 80% of mammalian families. We find that regions of reduced genetic diversity are more abundant in species at a high risk of extinction, discern signals of evolutionary selection at high resolution and provide insights from individual reference genomes. By prioritizing phylogenetic diversity and making data available quickly and without restriction, the Zoonomia Project aims to support biological discovery, medical research and the conservation of biodiversity.
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Terms of Use
Creative Commons Attribution 4.0 International license
https://creativecommons.org/licenses/by/4.0/
Persistent DSpace Link
https://hdl.handle.net/1721.1/134633
DOI of Published Version
10.1038/s41586-020-2876-6
