Cellular biophysical markers of hydroxyurea treatment in sickle cell disease
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1025103.pdf
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Author(s)
Du, E.
Papageorgiou, Dimitrios P.
Higgins, John
Kato, Gregory J.
Suresh, Subra
So, Peter T. C.
Hosseini, Poorya
Abidi, Sabia
Dao, Ming
Yaqoob, Zahid
Date Issued
April 2017
Journal
Proceedings Volume 10251, Biomedical Imaging and Sensing Conference
Publisher
SPIE
Citation
So, Peter T. C., et al. "Cellular Biophysical Markers of Hydroxyurea Treatment in Sickle Cell Disease." Proceedings Volume 10251, Biomedical Imaging and Sensing Conference, 19-21 April, 2017, Yokohama, Japan, edited by Toyohiko Yatagai et al., SPIE, 2017, p. 1025103. © 2017 SPIE.
Version
Final published version
Abstract
Using a common-path interferometric technique, we measure biomechanical and morphological properties of individual red blood cells in SCD patients as a function of cell density, and investigate the correlation of these biophysical properties with drug intake as well as other clinically measured parameters.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Chemistry
Massachusetts Institute of Technology. Department of Mechanical Engineering
Massachusetts Institute of Technology. Laser Biomedical Research Center
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1117/12.2273139
