5.32 Intermediate Chemical Experimentation, Spring 2003
Author(s)
Gheorghiu, Mircea
Klibanov, Alexander
Alternative Title
Intermediate Chemical Experimentation
Date Issued
June 2003
Abstract
5.32 involves more advanced experimental work than 5.310 or 5.311. The course emphasizes organic synthesis assisted by chiral catalysis, purification, and analysis of organic compounds employing such methods as IR, 1D and 2D NMR, UV spectroscopies and mass spectrometry, and thin layer and non-chiral and chiral gas chromatography. In 5.32, experiments also involve enzyme purification, characterization and assays, as well as molecular modeling in organic synthesis and in biochemical systems. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented. Legal Notice
Subjects
intermediate chemical experimentation
experiment
chemistry
organic synthesis
chiral catalysis
purification
organic chemistry
laboratory
IR
1D NMR
2D NMR
UV spectroscopy
mass spectrometry
thin layer gas chromatography
non-chiral gas chromatography
chiral gas chromatography
enzyme purification
characterization
assays
molecular modeling
organic synthesis
biochemical systems
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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