Working Memory: Delay Activity, Yes! Persistent Activity? Maybe Not
Name
7013.full.pdf
Description
Published version
Size
169.84 KB
Format
Unknown
Checksum (MD5)
856a333c065c0ee4929617ba4e91c0df
Author(s)
Lundqvist, Lars Mikael
Herman, Pawel
Miller, Earl K
Date Issued
2018
Journal
Journal of Neuroscience
Publisher
Society for Neuroscience
Version
Final published version
Abstract
© 2018 the authors. Persistent spiking has been thought to underlie working memory (WM). However, virtually all of the evidence for this comes from studies that averaged spiking across time and across trials, which masks the details. On single trials, activity often occurs in sparse transient bursts. This has important computational and functional advantages. In addition, examination of more complex tasks reveals neural coding in WM is dynamic over the course of a trial. All this suggests that spiking is important for WM, but that its role is more complex than simply persistent spiking.
MIT Department
Picower Institute for Learning and Memory
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1523/JNEUROSCI.2485-17.2018
