The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2
Name
1-s2.0-S2589004221002728-main.pdf
Description
Published version
Size
1.21 MB
Format
Adobe PDF
Checksum (MD5)
bec4cf816cf98480f73aa611f52bba86
Author(s)
Mahoney, Andrew R.
Safaee, Mohammad Moein
Wuest, William M.
Furst, Ariel L.
Date Issued
March 2021
Journal
iScience
Publisher
Elsevier BV
Citation
Mahoney, Andrew R. et al. "The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2." iScience 24, 4 (April 2021): 102304 © 2021 The Authors
Version
Final published version
Abstract
The ongoing SARS-CoV-2 pandemic has highlighted the importance of the rapid development of vaccines and antivirals. However, the potential for the emergence of antibiotic resistances due to the increased use of antibacterial cleaning products and therapeutics presents an additional, underreported threat. Most antibacterial cleaners contain simple quaternary ammonium compounds (QACs), however these compounds are steadily becoming less effective as antibacterial agents. QACs are extensively used in SARS-CoV-2 related sanitization in clinical and household settings. Similarly, due to the danger of secondary infections, antibiotic therapeutics are increasingly used as a component of COVID-19 treatment regimens, even in the absence of a bacterial infection diagnosis. The increased use of antibacterial agents as cleaners and therapeutics is anticipated to lead to novel resistances in the coming years.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.isci.2021.102304
