Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome
Name
nihms821328.pdf
Description
Accepted version
Size
612.96 KB
Format
Adobe PDF
Checksum (MD5)
b722685bddc82e60c0bf64895c751735
Author(s)
Anselmo, Aaron C
McHugh, Kevin J
Webster, Jamie
Langer, Robert
Jaklenec, Ana
Date Issued
2016
Journal
Advanced Materials
Publisher
Wiley
Citation
Anselmo, A. C., et al. "Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome." Adv Mater (2016).
Version
Author's final manuscript
Abstract
The gastrointestinal (GI) microbiome is widely investigated for its role in many diseases. However, technologies designed for microbiome delivery are lacking. Here, a layer-by-layer (LbL) approach is reported for probiotic encapsulation to protect probiotics against GI tract insults and improve their adhesion and growth on the intestines. These advantages translate to significantly enhanced survival of LbL-probiotics in vivo.
MIT Department
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1002/ADMA.201603270
