Wide-field extended-resolution fluorescence microscopy with standing surface plasmon resonance waves
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so_wide-fieldextended.pdf
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Author(s)
Kim, Yang-Hyo
Tang, Wai Teng
So, Peter T. C.
Chung, Euiheon
Sheppard, Colin J. R.
Alternative Title
Wide-field extended-resolution fluorescence microscopy with standing surface-plasmon-resonance waves
Date Issued
July 2009
Journal
Optics Letters
Publisher
Optical Society of America
Citation
Euiheon Chung, Yang-Hyo Kim, Wai Teng Tang, Colin J. R. Sheppard, and Peter T. C. So, "Wide-field extended-resolution fluorescence microscopy with standing surface-plasmon-resonance waves," Opt. Lett. 34, 2366-2368 (2009)
Version
Author's final manuscript
Abstract
The resolution of conventional SPR imaging has been limited by the diffraction nature of light. A wide-field extended-resolution optical imaging technique, standing-wave surface plasmon resonance fluorescence (SW-SPRF) microscopy, has been developed. Based on evanescent SPR standing waves, SW-SPRF provides lateral resolution approaching 100 nm and offers the advantages of significant signal enhancement and background noise reduction. SW-SPRF has the potential for sensitive biomolecular detection, nanoscale imaging, and lithographic applications.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Mechanical Engineering
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1364/OL.34.002366
