Oxygen levels in thermoplastic microfluidic devices during cell culture
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Kamm_Oxygen levels.pdf
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Author(s) • • •
Ochs, Christopher J.
Kasuya, Junichi
Pavesi, Andrea
Kamm, Roger Dale
Date Issued
November 2013
Journal
Lab on a Chip
Publisher
Royal Society of Chemistry
Citation
Ochs, Christopher J., Junichi Kasuya, Andrea Pavesi, and Roger D. Kamm. “Oxygen Levels in Thermoplastic Microfluidic Devices During Cell Culture.” Lab Chip 14, no. 3 (2014): 459–462.
Version
Author's final manuscript
Abstract
We developed a computational model to predict oxygen levels in microfluidic plastic devices during cell culture. This model is based on experimental evaluation of oxygen levels. Conditions are determined that provide adequate oxygen supply to two cell types, hepatocytes and endothelial cells, either by diffusion through the plastic device, or by supplying a low flow rate of medium.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1039/c3lc51160j