Connecting the study of wild influenza with the potential for pandemic disease
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Runstadler_Connecting the.pdf
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Author(s)
Runstadler, Jonathan
Keogh, Mandy
Hill, Nichola J.
Hussein, Islam
Puryear, Wendy Blay
Date Issued
March 2013
Journal
Infection, Genetics and Evolution
Publisher
Elsevier
Citation
Runstadler, Jonathan, Nichola Hill, Islam T.M. Hussein, Wendy Puryear, and Mandy Keogh. “Connecting the Study of Wild Influenza with the Potential for Pandemic Disease.” Infection, Genetics and Evolution 17 (July 2013): 162–187.
Version
Author's final manuscript
Abstract
Continuing outbreaks of pathogenic (H5N1) and pandemic (SOIVH1N1) influenza have underscored the need to understand the origin, characteristics, and evolution of novel influenza A virus (IAV) variants that pose a threat to human health. In the last 4–5 years, focus has been placed on the organization of large-scale surveillance programs to examine the phylogenetics of avian influenza virus (AIV) and host–virus relationships in domestic and wild animals. Here we review the current gaps in wild animal and environmental surveillance and the current understanding of genetic signatures in potentially pandemic strains.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Division of Comparative Medicine
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1016/j.meegid.2013.02.020
