Antiviral and Antibacterial Polyurethanes of Various Modalities
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12010_2012_Article_9999.pdf
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Author(s)
Park, Daewon
Wang, Yadong
Larson, Alyssa Maxine
Klibanov, Alexander M
Date Issued
January 2013
Journal
Applied Biochemistry and Biotechnology
Publisher
Springer-Verlag
Citation
Park, Daewon, Alyssa M. Larson, Alexander M. Klibanov, and Yadong Wang. “Antiviral and Antibacterial Polyurethanes of Various Modalities.” Applied Biochemistry and Biotechnology 169, no. 4 (January 10, 2013): 1134–1146.
Version
Author's final manuscript
Abstract
We have prepared and characterized a new polyurethane-based antimicrobial material, N,N-dodecyl,methyl-polyurethane (Quat-12-PU). It exhibits strong antiviral and antibacterial activities when coated (as an organic solution or an aqueous nanosuspension) onto surfaces and antibacterial activity when electrospun into nanofibers. Quat-12-PU surfaces are able to kill airborne Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli bacteria, as well as inactivate the enveloped influenza virus (but not the non-enveloped poliovirus).
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Chemistry
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1007/s12010-012-9999-7
