The injury response to DNA damage in live tumor cells promotes antitumor immunity
Name
nihms-1761610.pdf
Description
Accepted version
Size
2.53 MB
Format
Adobe PDF
Checksum (MD5)
e1edada19ac865237f9b16e0ecdeb4ab
Author(s)
Sriram, Ganapathy
Milling, Lauren E
Chen, Jung-Kuei
Kong, Yi Wen
Joughin, Brian A
Abraham, Wuhbet
Swartwout, Susanne
Handly, Erika D
Irvine, Darrell J
Yaffe, Michael B
Date Issued
2021
Journal
Science Signaling
Publisher
American Association for the Advancement of Science (AAAS)
Citation
Sriram, Ganapathy, Milling, Lauren E, Chen, Jung-Kuei, Kong, Yi Wen, Joughin, Brian A et al. 2021. "The injury response to DNA damage in live tumor cells promotes antitumor immunity." Science Signaling, 14 (705).
Version
Author's final manuscript
Abstract
Inducing a DNA damage response in tumor cells ex vivo creates an immunogenic live-cell adjuvant.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1126/SCISIGNAL.ABC4764
