Eradicating Bacterial Persisters with Combinations of Strongly and Weakly Metabolism-Dependent Antibiotics
Name
1-s2.0-S2451945620303378-main.pdf
Description
Published version
Size
1.22 MB
Format
Adobe PDF
Checksum (MD5)
06aa778a5e3cdbb4d69d96591990eeb3
Author(s)
Zheng, Erica J
Stokes, Jonathan M
Collins, James J
Date Issued
2020
Journal
Cell Chemical Biology
Publisher
Elsevier BV
Version
Final published version
Abstract
© 2020 The Authors Zheng et al. rationally combine antibiotics using insights on bacterial metabolism to identify drug-drug combinations that sterilize bacterial cultures of both metabolically active and persister cells, while dose-sparing toxic antibiotics.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Harvard University--MIT Division of Health Sciences and Technology
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/J.CHEMBIOL.2020.08.015
