Rhythmic neuronal synchronization in visual cortex entails spatial phase relation diversity that is modulated by stimulation and attention
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Desimone_Rhythmic neuronal.pdf
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Author(s)
Maris, Eric
Womelsdorf, Thilo
Desimone, Robert
Fries, Pascal
Date Issued
February 2013
Journal
NeuroImage
Publisher
Elsevier
Citation
Maris, Eric, Thilo Womelsdorf, Robert Desimone, and Pascal Fries. “Rhythmic Neuronal Synchronization in Visual Cortex Entails Spatial Phase Relation Diversity That Is Modulated by Stimulation and Attention.” NeuroImage 74 (July 2013): 99–116.
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Author's final manuscript
Abstract
Groups of neurons tend to synchronize in distinct frequency bands. Within a given frequency band, synchronization is defined as the consistency of phase relations between site pairs, over time. This synchronization has been investigated in numerous studies and has been found to be modulated by sensory stimulation or cognitive conditions. Here, we investigate local field potentials (LFPs) and multi-unit activity (MUA) recorded from area V4 of two monkeys performing a selective visual attention task. We show that phase relations, that are consistent over time, are typically diverse across site pairs. That is, across site pairs, mean phase relations differ substantially and this across-site-pair phase-relation diversity (SPHARED, for Spatial PHAse RElation Diversity) is highly reliable. Furthermore, we show that visual stimulation and selective attention can shift the pattern of phase relations across site pairs. These shifts are again diverse and this across-site-pair phase-relation-shift diversity (SPHARESD) is again highly reliable. We find SPHARED for LFP–LFP, LFP–MUA and MUA–MUA pairs, stimulus-induced SPHARESD for LFP–LFP and LFP–MUA pairs, and attention-induced SPHARESD for LFP–LFP pairs. SPHARESD is a highly interesting signal from the perspective of impact on downstream neuronal activity. We provide several pieces of evidence for such a role.
MIT Department
McGovern Institute for Brain Research at MIT
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Creative Commons Attribution-NonCommercial-NoDerivs License
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DOI of Published Version
https://doi.org/10.1016/j.neuroimage.2013.02.007
